Multiple Myeloma Cancer is Triggered By Mutated Genes, Say ...

A recent study has found that mutated genes trigger cancer in almost 33% of the multiple myeloma cancer patients. The study was conducted by researchers from the Institute of Cancer Research (ICR). It is believed that the findings of the study could improve the diagnosis and treatment of multiple myeloma.

Multiple myeloma is cancer which is located in the bone marrow. A person affected with this particular cancer may show symptoms of anemia, weaken immune system and unusual bleeding. It is considered to me most aggressive form of cancer.

In the US, it is estimated that every year about 4,000 patients are diagnosed with it. The cancer is aggressive in nature, so much so that even intense treatment fails in increasing the life expectancy of the patients. A patient infected with the cancer lives for maximum of five years after being diagnosed with it.

According to the study, the family members of the multiple myeloma cancer patients have four times higher chances of developing the cancer. Although it is known that multiple myeloma cancer is transmitted from one generation to other, it is for the very first time when researchers have claimed to have found genome responsible for triggering it.

For the study, the researchers compared the DNA of 1,675 multiple myeloma cancer patients with the DNA of 5,900 healthy people. During the study, the researchers found two genomes which were present in almost all the multiple myeloma cancer patients.

While acknowledging the findings of the study, Eric Low, Chief Executive of Myeloma UK, said, ?Understanding the biological and genetic basis for the onset and progression of myeloma is extremely important and will lead to better screening, earlier diagnosis and treatment in the future?. It is hoped that soon the researchers would be able to find a cure of the deadly cancer.

Source: http://topnews.us/content/244933-multiple-myeloma-cancer-triggered-mutated-genes-say-researchers

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Hotel explosion kills 3, wounds 27 in Philippines (AP)

MANILA, Philippines ? A powerful blast killed at least 3 people and wounded 27 others in a budget hotel packed with wedding guests in the southern Philippines, officials said Monday.

The explosion, suspected to have been caused by a bomb, ignited a fire that gutted the two-story Atilano Pension House in downtown Zamboanga city late Sunday.

The blast was so powerful it caused much of the second floor to collapse, blew off the hotel roof and shattered glass panes and windows from nearby buildings, Zamboanga city Mayor Celso Lobregat said.

Two of the wounded were in serious condition in a hospital, he said.

Zamboanga city, a predominantly Christian trading hub 540 miles (860 kilometers) south of Manila, is located in a volatile region long troubled by a decades-long Muslim insurgency, extortion gangs and kidnap for ransom syndicates.

The blast occurred in room 226 on the second floor of the hotel, instantly killing two people staying in two adjacent rooms, which were devastated by the blast. A third body was found Monday on the ground floor, pinned by the cement slabs that collapsed from above.

Initial investigation pointed to a bomb, Lobregat said, adding that he has asked Zamboanga residents to stay calm.

"We should not show that we're panicking because that is what these troublemakers relish to see," Lobregat told The Associated Press by telephone. "We have good leads; we will get all of them."

Many of the victims were from a group of about 20 people, who occupied six of the hotel's 35 rooms for a wedding on Monday. The tragedy has forced the wedding to be postponed, he said.

Senior Inspector Cesar Memoracion said his local bomb squad recently informed the hotel owner to be on guard for a possible bomb attack, citing intelligence, which did not identify the source of the threat.

In January 2000, the hotel was rocked by a blast that killed three suspected Muslim militants assembling a bomb in a room, officials said.

Source: http://us.rd.yahoo.com/dailynews/rss/asia/*http%3A//news.yahoo.com/s/ap/20111128/ap_on_re_as/as_philippines_hotel_explosion

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Germany: 20 police injured during nuke protest

BERLIN?? German police say 20 policemen have been injured during clashes with protesters ahead of the arrival of a shipment of nuclear waste in northern Germany.

Police say some 300 protesters threw stones and fireworks at security officers near the town of Dannenberg Saturday.

It followed a clash on Friday night when police used water cannons and batons to keep some 200 protesters in check. The officers were injured during the clash.

The protests occurred near the railway tracks used by a train this weekend to transport the nuclear waste shipment reprocessed in France to a storage site near the town of Gorleben.

Some 20,000 officers are on hand in the region to secure the shipment.

Officials have yet to resolve where such waste should be stored permanently. Activists say Gorleben is unsafe.

Copyright 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://www.msnbc.msn.com/id/45443901/ns/us_news-environment/

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